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Shannon Hogan, PhD

Assistant Professor

Watson-Hubbard Science Center
Department STEM

Mailing Address

Regis College

235 Wellesley Street
Weston, MA 02493

About

Dr. Hogan, an assistant professor in the STEM department at Regis, began his career as a senior scientist for IDEXX Laboratories, a principal scientist at Dyax Corp., a Consultant at Adnexus Pharmaceuticals, and a Visiting Scientist at Harvard Medical School, before applying his professional experience to teaching in higher education. Prior to joining Regis College, he also served as an adjunct professor in the biology departments at Boston College and Emmanuel College.

As an experienced educator and scientist, he's played an active role in teaching and mentoring undergraduate and graduate students at the university level and in the biotechnology industry throughout his career. Dr. Hogan's teaching focuses on preparing students for their future careers in graduate school, medical school, or the industrial sector.

For his PhD, Dr. Hogan designed assays that were highly accurate in identifying and quantifying RNA viruses in drinking water. After graduate school, he went into the biotechnology industry for 14 years. There, he spent the majority of his time designing technology that served to produce biotherapeutics for cancer and autoimmune diseases. He have a number of journal articles, posters, and patents representing this work.

At Regis, Dr. Hogan teaches a variety of courses including, but not limited to, virology, environmental microbiology, and microbiology. He is also the lead professor for the Laboratory Operations Management (LOM) minor. LOM courses focus on biological and chemical safety as well as the handling and care of animals. The course also focuses on students obtaining online certifications and cover letter and resume writing. Students are trained to prepare these documents and apply to jobs in both academic and industrial sectors. Through these courses, students have obtained positions at Weill Cornell Medical School, The Innovation Institute, Evelo Biosciences, Senda Biosciences, Boston Children’s Hospital, ScribeAmerica, as well as other industry and academic related positions.

Education

PhD, Virology, University of New Hampshire, 1998

Devy L, Huang L, Naa L, Yanamandra N, Pieters H, Frans N, Chang E, Tao Q, Vanhove M, Lejeune A, van Gool R, Sexton DJ, Kuang G, Rank D, Hogan S, Pazmany C, Ma YL, Schoonbroodt S, Nixon AE, Ladner RC, Hoet R, Henderikx P, Tenhoor C, Rabbani SA, Valentino ML, Wood CR, Dransfield DT. 2009. Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis. Cancer Res. 69(4):1517-26.

Chen T, Hogan S, Conley G, Pazmany C, Wu QL, McNeil GL, Bassill G, Macintyre AN, Martik D, Nixon AE, Sexton DJ. 2007. Discovery and characterization of human antibody inhibitors of pregnancy-associated plasma protein-A. Biol. Chem. 388(5):507-12.

Wassaf D, Kuang G, Kopacz K, Wu QL, Nguyen Q, Toews M, Cosic J, Jacques J, Wiltshire S, Lambert J, Pazmany CC, Hogan S, Ladner RC, Nixon AE, Sexton DJ. 2006. High-throughput affinity ranking of antibodies using surface plasmon resonance microarrays. Anal Biochem. 351(2): 241-53.

Hogan, S., Rookey, K., Ladner, R. 2005. URSA: ultra rapid selection of antibodies from an antibody phage display library. Biotechniques 38(4): 536-538.

Hoet, R.M., Cohen, E.H., Kent, R.B., Rookey, K., Schoonbroodt, S., Hogan, S., Rem, L., Frans, N., Daukandt, M., Pieters, H., van Hegelsom, R., Neer, N.C., Nastri, H.G., Rondon, I.J., Leeds, J.A., Hufton, S.E., Huang, L., Kashin, I., Devlin, M., Kuang, G., Steukers, M., Viswanathan, M., Nixon, A.E., Sexton, D.J., Hoogenboom, H.R., Ladner, R.C. 2005. Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. Nat Biotechnol. 23(3): 344-8.

Patents

Ladner, Robert C., Hogan, Shannon, and Rookey, Kristin. US Patent No. 8,557,743: Display Library Process, September 16, 2004. The invention describes methods for identifying desired members from display libraries. Display library members can be amplified in the presence of a target compound so that cycles of selection can be rapidly completed.

Posters

Shannon Hogan, Jennifer Marra, Molly Belles, Dexter Jeanty, Laura Kunz. Virology Laboratory Curriculum Development. 2020 Wheaton College Women in Stem Conference (postponed)

Shannon Hogan, Jennifer Marra, Molly Belles, Dexter Jeanty, Laura Kunz. Virology Laboratory Curriculum Development. 2019 Next-In Bio

Shannon Hogan, Jennifer Marra, Molly Belles, Dexter Jeanty, Laura Kunz. Virology Laboratory Curriculum Development. 2019 Regis College Let It Shine Gala. This work was supported by a faculty development grant from Regis College.

Paul Brand, Meagan Cherry, Corinne Decicco, Katelyn Guill, Matthew McCarthy, Shayna Miller, Mariah Ramdial, Andrew Vitolo, Jenna Whalen and Shannon Hogan. Developing a Student Lab to Investigate Biodiesel and Bioethanol Production: Integrating Key Concepts from Plant Biology, Biochemistry, and Organic Chemistry. 2014, 8th Annual Muddy River Research Symposium. Received Certificate of Excellence.

Shannon Hogan, Shauna Mason, Gary Bassill, Cuong Tran, Kristin Rookey, Malini Viswanathan, Ziggy Demyt, Greg Conley, Diana Martik, Dan Sexton. Identification of Rabbit and Sheep Tissue Kallikrein 1 Sequences. 2008 PEGS Conference.

Shauna Mason, Annie Woodland, Brian Ciulla, Matthew Gollwitzer, Deirdre Vaughn, Judy Jacques, Shannon Hogan 2007. Development of a Quantitative PCR Method for the Detection of Pichia pastoris Genomic DNA in the Validation of Drug Candidate Manufacturing. 2006 CHI Quantitative PCR Conference

Gregory P. Conley, Csaba C. Pazmany, Shannon Hogan, Farrah Chaudhary, Robert Patterson, Judy Healy, Que Nguyen, Daniel J. Sexton and Andrew E. Nixon. Analysis of Expression Systems for Production of a Biologically Active Tissue Kallikrein. 2005 CHI Pep Talk Conference.

Ginger Chen, Shannon Hogan, Andy Nixon, Greg Conley, Dan Sexton. Discovery and Biochemical Characterization of Human Antibody Inhibitors of the Protease Activity of Pregnancy-Associated Plasma Protein-A. 2004 ASBMB Conference.

S. Hogan and S. Spatz. DNA Probe Assay for the Detection of Mycobacterium paratuberculosis in Bovine. 2000 New England Regional AAVLD Conference.

K. Velek, S. Hogan, and H. Liauw. ELISA for the Detection of Antibodies to Swine Influenza Virus in Swine Sera. 2000 Allen D. Leman Swine Conference.

H. Liauw, K. Velek, S. Hogan. Development of an ELISA for the Detection of Mycoplasma pneumoniae in Swine. 2000 Allen D. Leman Swine Conference.

S. Hogan, L. Bergeron, L. Plourde, and S. Spatz. An Improved DNA Probe Assay to Detect Mycobacterium paratuberculosis in Bovine Feces: Development of an Internal Probe to Assess the Presence of PCR Inhibitors in a Nucleic Acid-Based Assay. 1999 National AAVLD Conference.

K. Velek, S. Hogan, and H. Liauw. Development of an ELISA for the Detection of Antibodies to Swine Influenza Virus in Swine Sera. 1999 National AAVLD Conference.