Amy Knapp

Assistant Professor

t 781-768-7367


PhD Biomedical Sciences, University of California, San Diego

BS Biological Sciences, University of California, Davis, CA


Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise. J Biol Chem. 2011 Sep 2;286(35):30561-70.

Stary, C.M., B.J. Walsh, A.E. Knapp, D. Brafman, and M.C. Hogan. Elevation in heat shock protein 72 mRNA following contractions in isolated single skeletal muscle fibers. Am J Physiol Regul Integr Comp Physiol. 2008 Aug;295(2):R642-8.

Breen, E., K. Tang, M. Olfert, A. Knapp, and P.D. Wagner P. Skeletal muscle capillarity during hypoxia: VEGF and its activation. High Alt Med Biol. 2008 Summer;9(2):158-66.

Olfert, M., J. Balouch, A. Kleinsasser, A. Knapp, H. Wagner, P.D. Wagner, and S.R. Hopkins. Does gender affect human pulmonary gas exchange during exercise? J Physiol. Volume 557, Number 2, 529-541, June 1, 2004.

Publications in preparation

Amy E. Knapp, Hamid Delavar, Daniel Goldberg, Kechun Tang, Michael C. Hogan, Peter D. Wagner, Pierre Chambon and Daniel Metzger, and Ellen C. Breen. Skeletal muscle myofiber-expressed VEGF regulates contraction-induced blood flow and exercise capacity but not muscle capillarity in cage-confined adult mice.


Leonardo Nogueira, Amy E. Knapp, and Michael C. Hogan. Phenol increases twitch tension by increasing Ca2+ transients in intact single Xenopus myofibers. FASEB J. 2010 24: 1048.10

Amy E. Knapp, Kechun Tang, Michael C. Hogan, Peter D. Wagner, Ellen C. Breen. Skeletal Myocyte-Specific VEGF Gene Deletion in Adult Mice Leads to Impaired Exercise Capacity without Evidence of Capillary Regression or Altered In Vitro Muscle Contraction. ACSM National Meeting, Seattle, May 2009.

Amy E. Knapp, Kechun Tang, Michael C. Hogan, Peter D. Wagner, Ellen C. Breen. Skeletal Myocyte-Specific VEGF Gene Deletion in Adult, Cage-confined Mice Does Not Affect Muscle Capillarity. American Thoracic Society Meeting, San Diego, April 2009. Creed M. Stary, Richard A Howlett, David Brafman, Amy E. Knapp, Brandon Walsh and Michael C. Hogan. Calcium is an Activator of Heat Shock Protein 72 Transcription in Isolated Single Skeletal Muscle Fibers of Xenopus laevis During Contractions. APS Intersociety Meeting: The Integrative Biology of Exercise V, September 2008.

Amy E Knapp, Michael C Hogan, Peter D Wagner, and Ellen C Breen.  Hydrogen Peroxide- Induced VEGF Transcription in C2C12 Myoblasts is Dependent on the Oxygen Environment. 2007.  FASEB J. 21: 769.22.

Stary, C.M., B. Walsh, A.E. Knapp, M.C. Hogan. Elevation of Heat Shock Protein 72 mRNA in Contracting Single Xenopus Muscle Fibers is Fiber Type- and not Fatigue-Dependent. ACSM National Meeting, New Orleans, May 2007.

Walsh, B., C.M. Stary, A.E. Knapp, M.C. Hogan. Measurement of Heat Shock Protein 72 mRNA Following Fatiguing Contractions in Isolated Single Skeletal Muscle Fibers. ACSM National Meeting, New Orleans, May 2007.

Oral Presentations

Kechun Tang, Amy Knapp, Peter Wagner, and Ellen Breen. Ischemia/Reperfusion-Induced VEGF Transcription in Mouse Skeletal Muscle. 2007. FASEB J. 21: 35.4

Research Interests

Regulation of capillary growth in skeletal muscle in health and disease, skeletal muscle physiology, exercise physiology

Biology Department

t 781-768-7447

Mailing Address

Regis College
Science Building
235 Wellesley Street
Weston, MA 02493
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